At UC Irvine
Discovering microbiota functions via chemical probe incorporation for targeted sequencing.
Falco N, Griffin ME. Current Opinion in Chemical Biology. In press.
Microbial mechanisms to improve immune checkpoint blockade responsiveness.
Griffin ME†, Hang HC†. Neoplasia 31 (2022): 100818. † co-corresponding author. Pubmed
Tools for mammalian glycoscience research.
Griffin ME, Hsieh-Wilson LC. Cell 185 (2022): 2657-2677. Pubmed
Before UC Irvine
Functional glycoproteomics by integrated network assembly and partitioning.
Griffin ME*†, Thompson JW*, Xiao Y*, Sweredoski MJ, Aksenfeld RB, Jensen EH, Koldoskaya Y, Schacht AL, Kim TD, Choudhry P, Lomenick B, Garbis SD, Moradian A, Hsieh-Wilson LC†. Preprint. Online: June 14, 2023. * equal contribution, † co-corresponding author. bioRxiv
Chemical immunology.
Griffin ME, Teijaro J, Hang HC. in Advanced chemical biology: chemical dissection and reprogramming of biological systems.
Eds. Hang HC, Pratt MR, Prescher JA. Wiley (2023): 669-688. Wiley
N-arylpyrazole NOD2 agonists promote immune checkpoint inhibitor treatment.
Griffin ME*, Tsukidate T*, Hang HC. ACS Chem. Biol. 18 (2023): 1368-1377. * equal contribution. Pubmed
Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions.
Griffin ME*, Klupt S*, Espinosa J*, Hang HC. Cell Chem. Biol. 30 (2023): 436-456. * equal contribution. Pubmed
Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization.
Jang KK, Heaney T, London M, Ding Y, Yeung F, Ercelen D, Chen Y-C, Axelrad J, Gurunathan S, Keestra-Gounder AM, Griffin ME, Hang HC, Cadwell K. Preprint. Online: 2023 Feb 1. bioRxiv
Improving immunotherapy response through the use of designer bacteria.
Griffin ME, Hang HC. Cancer Cell. 39 (2021): 1576-1577. Pubmed
Enterococcus peptidoglycan remodeling promotes checkpoint inhibitor cancer immunotherapy.
Griffin ME, Espinosa J, Becker JL, Luo JD, Carroll TS, Jha JK, Fanger GR, Hang HC. Science. 373 (2021): 1040-1046. Pubmed
RecT recombinase expression enables efficient gene editing in Enterococcus spp.
Chen V, Griffin ME, Maguin P, Varble A, Hang HC. Appl. Environ. Microbiol. 87 (2021): e0084421. Pubmed
Sulfated glycans engage the Ang-Tie pathway to regulate vascular development.
Griffin ME, Sorum AW, Miller GM, Goddard WA 3rd, Hsieh-Wilson LC. Nat. Chem. Biol. 17 (2021): 178-186. Pubmed
Translation of peptidoglycan metabolites into immunotherapeutics.
Griffin ME, Hespen CW, Wang YC, Hang HC. Clin. Transl. Immunol. 8 (2019): e1095. Pubmed
Peptidoglycan metabolite photoaffinity reporters reveal direct binding to intracellular pattern recognition receptors and Arf GTPases.
Wang YC*, Westcott NP*, Griffin ME*, Hang HC. ACS Chem. Biol. 14 (2019): 405-414. * equal contribution. Pubmed
Methods for the detection, study, and dynamic profiling of O-GlcNAc glycosylation.
Thompson JW, Griffin ME, Hsieh-Wilson LC. Methods Enzymol. 598 (2018): 101-135. Pubmed
Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag.
Griffin ME, Jensen EH, Mason DE, Jenkins CL, Stone SE, Peters EC. Hsieh-Wilson LC. Mol. Biosyst. 12 (2016): 1756-1759. Pubmed
Glycan engineering for cell and developmental biology.
Griffin ME, Hsieh-Wilson LC. Cell Chem. Biol. 23 (2016): 108-121. Pubmed
Long-lived engineering. of glycans to direct stem cell fate.
Pulsipher A*, Griffin ME*, Stone SE, Hsieh-Wilson LC. Angew. Chem. Int. Ed. 54 (2015): 1466-1470. * equal contribution. Pubmed
Directing neuronal signaling through cell-surface glycan engineering.
Pulsipher A, Griffin ME, Stone SE, Brown JM, Hsieh-Wilson LC. J. Am. Chem. Soc. 136 (2014): 6794-6797. Pubmed
Improving biologic drugs via total chemical synthesis.
Hsieh-Wilson LC, Griffin ME. Science. 342 (2013): 1332-1333. Pubmed
Synthetic probes of glycosaminoglycan function.
Griffin ME, Hsieh-Wilson LC. Curr. Opin. Chem. Biol. 17 (2013): 1014-1022. Pubmed
Molecular recognition and enhancement of aqueous solubility and bioactivity of CD437 by β-cyclodextrin.
Misher RJ, Griffin ME, Battle CH, Shan B, Jayawickramarajah J. Bioorg. Med. Chem. Lett. 21 (2011): 857-860. Pubmed