At UC Irvine

Microbial mechanisms to improve immune checkpoint blockade responsiveness.
Griffin ME†, Hang HC†. Neoplasia 31 (2022): 100818. † co-corresponding author. Pubmed

Tools for mammalian glycoscience research.
Griffin ME, Hsieh-Wilson LC. Cell 185 (2022): 2657-2677. Pubmed

Before UC Irvine


Functional glycoproteomics by integrated network assembly and partitioning.
Griffin ME*†, Thompson JW*, Xiao Y*, Sweredoski MJ, Aksenfeld RB, Jensen EH, Koldoskaya Y, Schacht AL, Kim TD, Choudhry P, Lomenick B, Garbis SD, Moradian A, Hsieh-Wilson LC†. Preprint. Online: June 14, 2023. * equal contribution, † co-corresponding author. bioRxiv

Chemical immunology.
Griffin ME, Teijaro J, Hang HC. in Advanced chemical biology: chemical dissection and reprogramming of biological systems.
Eds. Hang HC, Pratt MR, Prescher JA. Wiley (2023): 669-688. Wiley

N-arylpyrazole NOD2 agonists promote immune checkpoint inhibitor treatment.
Griffin ME*, Tsukidate T*, Hang HC. ACS Chem. Biol. 18 (2023): 1368-1377. * equal contribution. Pubmed

Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions.
Griffin ME*, Klupt S*, Espinosa J*, Hang HC. Cell Chem. Biol. 30 (2023): 436-456. * equal contribution. Pubmed

Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization.
Jang KK, Heaney T, London M, Ding Y, Yeung F, Ercelen D, Chen Y-C, Axelrad J, Gurunathan S, Keestra-Gounder AM, Griffin ME, Hang HC, Cadwell K. Preprint. Online: 2023 Feb 1. bioRxiv

Improving immunotherapy response through the use of designer bacteria.
Griffin ME, Hang HC. Cancer Cell. 39 (2021): 1576-1577. Pubmed

Enterococcus peptidoglycan remodeling promotes checkpoint inhibitor cancer immunotherapy.
Griffin ME, Espinosa J, Becker JL, Luo JD, Carroll TS, Jha JK, Fanger GR, Hang HC. Science. 373 (2021): 1040-1046. Pubmed

RecT recombinase expression enables efficient gene editing in Enterococcus spp.
Chen V, Griffin ME, Maguin P, Varble A, Hang HC. Appl. Environ. Microbiol. 87 (2021): e0084421. Pubmed

Sulfated glycans engage the Ang-Tie pathway to regulate vascular development.
Griffin ME, Sorum AW, Miller GM, Goddard WA 3rd, Hsieh-Wilson LC. Nat. Chem. Biol. 17 (2021): 178-186. Pubmed

Translation of peptidoglycan metabolites into immunotherapeutics.
Griffin ME, Hespen CW, Wang YC, Hang HC. Clin. Transl. Immunol. 8 (2019): e1095. Pubmed

Peptidoglycan metabolite photoaffinity reporters reveal direct binding to intracellular pattern recognition receptors and Arf GTPases.
Wang YC*, Westcott NP*, Griffin ME*, Hang HC. ACS Chem. Biol. 14 (2019): 405-414. * equal contribution. Pubmed

Methods for the detection, study, and dynamic profiling of O-GlcNAc glycosylation.
Thompson JW, Griffin ME, Hsieh-Wilson LC. Methods Enzymol. 598 (2018): 101-135. Pubmed

Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag.
Griffin ME, Jensen EH, Mason DE, Jenkins CL, Stone SE, Peters EC. Hsieh-Wilson LC. Mol. Biosyst. 12 (2016): 1756-1759. Pubmed

Glycan engineering for cell and developmental biology.
Griffin ME, Hsieh-Wilson LC. Cell Chem. Biol. 23 (2016): 108-121. Pubmed

Long-lived engineering. of glycans to direct stem cell fate.
Pulsipher A*, Griffin ME*, Stone SE, Hsieh-Wilson LC. Angew. Chem. Int. Ed. 54 (2015): 1466-1470. * equal contribution. Pubmed

Directing neuronal signaling through cell-surface glycan engineering.
Pulsipher A, Griffin ME, Stone SE, Brown JM, Hsieh-Wilson LC. J. Am. Chem. Soc. 136 (2014): 6794-6797. Pubmed

Improving biologic drugs via total chemical synthesis.
Hsieh-Wilson LC, Griffin ME. Science. 342 (2013): 1332-1333. Pubmed

Synthetic probes of glycosaminoglycan function.
Griffin ME, Hsieh-Wilson LC. Curr. Opin. Chem. Biol. 17 (2013): 1014-1022. Pubmed

Molecular recognition and enhancement of aqueous solubility and bioactivity of CD437 by β-cyclodextrin.
Misher RJ, Griffin ME, Battle CH, Shan B, Jayawickramarajah J. Bioorg. Med. Chem. Lett. 21 (2011): 857-860. Pubmed